The Fight against Malaria

In 2012 some 207 million people – more than 80 percent of them from Africa – contracted malaria. Around 627,000 of these people, including a large number of children under 5, subsequently died of the disease (Source “World Malaria Report”, WHO 2013). In several African countries, such as Ethiopia, Uganda, Zambia and Malawi, Bayer for many years has participated actively in the fight against malaria, which is transmitted by the Anopheles mosquito. Two projects give special grounds for hope. A bed net sets new standards in prophylaxis and in active substance research the foundations have been laid for a breakthrough in the fight against the insects which transmit malaria.

A woman is sleeping on a bed, protected by a bed net.Zoom image
Bed nets which are impregnated with an insecticide can help reduce infections by mosquitoes, which carry malaria, by up to 50 percent. The nets have to remain fully effective after 20 washes which corresponds to roughly three years use.

Declaring War on Malaria 

It happens thousands of times, night after night, in Africa: Anopheles mosquitoes settle on sleeping people, bite them and suck up their blood fiand in doing so transmit the malaria parasite. One bite is enough and the disease spreads through the body. Bayer declared war on malaria long ago.

 

The Environmental Science Business Group therefore offers a large number of products and strategies to control the vectors, including tabs containing the insecticidal active ingredient deltamethrin with which to impregnate bed nets, and formulations for fumigating houses.

 

Now Environmental Science has opened up a new chapter in the fight against malaria, focusing on mosquito nets. To protect people against the mosquitoes which transmit the disease, the World Health Organization (WHO) is promoting Long-Lasting Insecticidal Nets (LLINs), which have an insecticide incorporated into the fibers of the nets.

Bayer has played a key role in the development of insecticide-treated nets.Today, our insecticides are used in many nets.
The LifeNet™ is the logical progression

LifeNet®: Bayer's contribution to fighting back Malaria

With these, the chance of infection can be reduced by up to 50 percent. The WHO makes stringent demands on the nets. They have to remain fully effective after 20 washes - which corresponds to three years’ use. “We far exceed this requirement with our LifeNet™,” says Dr. Rainer Sonneck, Head of Product Development for Pest and Vector Control, not without some pride. The bed net which has been developed will withstand 35 washes and can be used for five years. It is also more tear-proof, softer and more user-friendly than other comparable products.

The reason for these improvements is that instead of polyester or polyethylene, the scientists have used polypropylene for the first time as the basis of the fabric. A use with which they had no previous experience whatsoever, emphasizes Rainer Sonneck. The first challenge was to produce thin polypropylene threads and then to scale this up for mass production. The weaving process then had to be adapted. Finally, a method of incorporating the insecticidal active substance directly into the polypropylene fibers had to be found.

With Long-Lasting Insecticidal Nets the risk of infection can be reduced by up to

50 %.

Environmental Science has opened up a new chapter in the fight against malaria, focusing on mosquito nets.
A woman is hanging a fresh washed mosquito net on a clothes line to dry.
With these, the chance of infection can be reduced by up to 50 percent.

For Ildem Bozkurt, Project Manager in the field of vector control at Environmental Science, the LifeNet™ represents a logical development: “Bayer has played a key role in the development of insecticide-treated nets. Today, our insecticides are used in a broad range of nets. The LifeNet™ is the logical progression.” The net is currently being tested by the WHO in Africa and India and preparations for market launch are also under way. Bayer is also working closely on another ambitious project with the Innovative Vector Control Consortium (IVCC), an affiliation of leading institutions in the field of product development and information systems for improved vector control. 

Facts & Figures

  • In 2012 an estimated 627,000 people, including a large number of children under 5, died of malaria (Source “World Malaria Report”, WHO 2013).
  • About half of the world’s population – 3.3 billion people – live in risk areas and are at risk of catching malaria. Low-income countries are aff ected particularly severely.
  • More and more active substances are becoming ineff ective as the malaria parasite becomes resistant to them.
  • The increase in the mean temperature level as a result of global climate change promotes the reproduction and spread of mosquitoes. This could result in another 40 to 60 million people globally being exposed to the risk of malaria infection.

Prevention

Vector control – control of the mosquitoes – is currently the most effective approach in the fight against malaria. The most effective measures include spraying insecticides inside dwellings and using insecticidetreated bed nets. These are traditionally soaked in a liquid containing pyrethroids – chemical derivatives of the natural substance pyrethrum, which occurs in chrysanthemums. Bayer has supplied one of these products for many years. New technologies can now be used to incorporate pyrethroid molecules directly into the fibers of the nets.

Last updated: January 4, 2016 Copyright © Bayer AG
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