Bayer to present advancements of radiology portfolio at ECR 2025

Berlin, February 20, 2025 – Bayer will present advancements of its comprehensive radiology portfolio at the 2025 European Congress of Radiology (ECR) taking place from February 26 - March 2, 2025, in Vienna, Austria. The focus will be on progress in the development pipeline for contrast agents and injectors as well as innovations in the area of digital and Artificial Intelligence (AI).

Several scientific sessions will provide new clinical results of gadoquatrane, Bayer’s investigational macrocyclic gadolinium-based contrast agent for contrast-enhanced magnetic resonance imaging (MRI), including late-breaking data from the pivotal Phase III study QUANTI CNS (Central Nervous System). These sessions follow the recent announcement of positive topline data of all pivotal Phase III studies, investigating gadoquatrane at a gadolinium dose of 0.04 mmol Gd/kg body weight compared to the macrocyclic GBCAs dosed at 0.1 mmol Gd/kg body weight.

·         QUANTI CNS Phase 3 Study Results: Efficacy and Safety of Gadoquatrane in Patients Undergoing Contrast-Enhanced MRI of the CNS (Central Nervous System) at Reduced Gadolinium Dose Compared to Standard of Care Macrocyclic GBCAs
CTiR 1 - Clinical Trials in Radiology 3, Wednesday, February 26, 8-9.30 am CET

·         Efficacy of Gadoquatrane, a Novel Low-Dose High Relaxivity Macrocyclic Gadolinium-based Contrast Agent, at 5-, 10- and 15-min Post Injection in Comparison to Gadobutrol for CNS CE-MRI
RPS 2211 - Contrast agents and energy sustainability in neuroimaging, Sunday, March 2, 2025, 89:00 am CET

Updates from MEDRAD™ Centargo CT Injection System

In line with Bayer’s commitment to cardiac imaging, the company introduces Centargo | Cardio at ECR, Bayer's injector package for Cardiac CT – including its award-winning MEDRAD™ Centargo CT Injection System, paired with premium clinical application service and a bespoke patient preparation video. Centargo | Cardio is crafted to empower imaging professionals with the ability to create a tailored Cardiac CT imaging practice for their institutions, to support high-quality imaging results, and a better patient care.

At the Research Presentation Session on Green Innovations, where radiographers are pioneering sustainable healthcare, Bayer will present insights from a MEDRAD™ Centargo study it conducted at the Centre d'Imagerie Medicale de Radiothérapie (CIMROD center) in France – addressing the re-evaluation of CT injectors after France transitioned its contrast product supply model in March last year:

MEDRAD™ Centargo: Insights from the CIMROD Experiment on Contrast Consumption, Efficiency, Patient Care and Environmental Impact
RPS 2014 – Saturday, March 1, 2025, 2:00 pm CET

Following EU CE marking in 2020, and FDA clearance for the US at the end of 2024, the product has already been launched in 51 markets to date and can now deliver value for radiology departments across the globe which are facing a shortage of radiology technologists coupled with a rising demand for medical imaging.

Innovation in Radiology AI and Digital

Bayer in Radiology recognized the potential of AI in radiology early on and continuously extends its related offerings – with the ultimate goal to help improve patient outcomes, and to support radiologists and their teams with everyday clinical tasks.

On the occasion of ECR, Bayer introduces Systalyze, a spin-off of MIT (Massachusetts Institute of Technology) led by Manya Ghobadi, as a new collaboration partner on Bayer’s AI Innovation Platform (AIIP) – that aims to support development teams at healthcare organizations and startups from idea to launch of AI-enabled software solutions. The collaboration focuses on leveraging Systalyze's advanced cloud compute optimization tools with the goal to enhance the efficiency, sustainability and scalability of AI-driven healthcare solutions. AIIP is Bayer’s new cloud-based software development platform that is developed with the vision to accelerate the creation, validation, and deployment of AI and machine learning (ML) applications for medical imaging. Built on Google Cloud technology, AIIP facilitates collaboration among industry, healthcare and data providers within a development environment, incorporating a robust security infrastructure and an optimized tech stack for imaging-based AI solutions. Notably, AIIP has already integrated various external data providers, along with public datasets, significantly simplifying the process of gathering high-quality medical imaging.

At ECR 2025, Bayer is also showcasing several examples from radiology suites throughout Europe that successfully adopted Calantic™ Digital Solutions in clinical routines: the Swiss university hospital Inselspital Bern, the renowned private medical imaging departments in the Auvergne Rhône-Alpes region Imapôle (Imagerie Médicale Lyon Villeurbanne), the French telemedicine network TéléDiag as well as the pilot of the Galician Health Service SERGAS from Spain.

Developed by radiologists for radiologists, Calantic Digital Solutions curates various third-party app solutions into a single convenient, cloud-based marketplace – vetted with Bayer's expertise, to ensure the feasibility and reliability of the apps offered, meeting the requirements of diverse healthcare organizations and aiming to enhance clinical workflows effectively.

Other Scientific Highlights from Bayer at ECR 2025

·         Preclinical Profile of a New Macrocyclic MRI Liver Agent
RPS 801 - Advances in liver imaging, Thursday, February 27, 2025, 10-11:00 am CET

·         Clinical Safety of Gadoxetate Disodium – Review of over 20 Years of Use and almost 12 Million Administrations
Online Poster

·         Speed, Energy, Concentration: New Possibilities for CT, New Possibilities for Contrast Agents
EFOMP – Wednesday, February 26, 11:30 am CET

·         DENSE-2: Supplemental Contrast-Enhanced Mammography and Abbreviated MRI Screening for Women with Extremely Dense Breasts (Investigator Initiated Research; IIR)
CTiR 11 - Clinical Trials in Radiology 1, Thursday, February 27, 4-5.30 pm CET

·         Application of Artificial Intelligence in Non-Invasive Cardiovascular Imaging: A Systematic Review and Meta-analysis
Poster No. C-19973

The activities at ECR reflect Bayer’s commitment as a leading company in key areas of radiology to unlock new opportunities and accelerate innovation for the benefit of patients while supporting radiologists and their teams in tackling current and future challenges.

About Bayer in Radiology
As a true life-science company with a heritage of over 100 years in radiology, Bayer is committed to providing excellence – from innovative products to high-quality services – to support efficient and optimized patient care. Bayer offers a leading portfolio of contrast media for computed tomography (CT), X-ray, and magnetic resonance imaging (MRI), along with devices for their precise administration, informatics solutions, and a medical imaging platform delivering access to applications, including those enabled by AI. Bayer’s radiology products generated about €2bn sales in 2023.

About Bayer
Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. In line with its mission, “Health for all, Hunger for none,” the company’s products and services are designed to help people and the planet thrive by supporting efforts to master the major challenges presented by a growing and aging global population. Bayer is committed to driving sustainable development and generating a positive impact with its businesses. At the same time, the Group aims to increase its earning power and create value through innovation and growth. The Bayer brand stands for trust, reliability and quality throughout the world. In fiscal 2023, the Group employed around 100,000 people and had sales of 47.6 billion euros. R&D expenses before special items amounted to 5.8 billion euros. For more information, go to www.bayer.com.

Find more information at https://pharma.bayer.com
Follow us on LinkedIn: Bayer | Pharmaceuticals
Follow us on Twitter: @BayerPharma

Forward-Looking Statements
This release may contain forward-looking statements based on current assumptions and forecasts made by Bayer management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer’s public reports which are available on the Bayer website at www.bayer.com. The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments.