Thrombosis is the formation of a blood clot inside a blood vessel, blocking a vein (venous thrombosis) or artery (arterial thrombosis).


Venous thromboembolism (VTE) is a condition in which a blood clot forms most often in the deep veins of the leg, groin or arm (known as deep vein thrombosis, DVT) and travels in the circulation, lodging in the lungs (known as pulmonary embolism, PE). Together, DVT and PE are known as VTE - a dangerous, potentially deadly medical condition1.


Thrombosis (VTE), including Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE), occurs at an annual incidence of about 1 per 1,000 adults. Rates increase sharply after about age 45 years and are slightly higher in men than women in older age. Major risk factors for thrombosis, other than age, include exogenous factors such as surgery, hospitalization, immobility, trauma, pregnancy and the puerperium and hormone use, and endogenous factors such as cancer, obesity, and inherited and acquired disorders of hypercoagulation2.


Type of Thrombosis1

  • Deep Vein Thrombosis (DVT) is a blood clot that forms in a deep vein, usually the leg, groin or arm. Symptoms of DVT include : pain, swelling, redness of the affected area, usually the leg and the skin may also be warm to the touch.
  • Pulmonary embolism (PE) : A blood clot that occurs when a DVT clot breaks free from a vein wall and travels to the lungs blocking some or all of the blood supply. PE can often be fatal. Symptoms of PE include: acute shortness of breath, chest pain, rapid heart rate, some people may also cough blood.
  • DVT + PE = VTE : DVT and PE are collectively referred to as VTE.


References :
2. 307_Epidemiology_and_Risk_Factors_for_Venou s_Thrombosis