Innovation

Development Pipeline

Development Pipeline

We are determined to drive breakthrough innovations for patients in diseases of high unmet medical need. In clinical development we are currently advancing more than 34 projects that we review regularly so that we can give priority to the most promising programs.

Pipeline Overview

The following table lists a selection of major Pharma portfolio projects that we are advancing through different stages of development. Click on a project for further information.

 

More detailed information on individual programs, therapeutic areas, and development timelines as well as a one-page overview of our development portfolio can be found in our overview package for download.

 

Phases

Number of programs in clinical development.

 

Download
Pipeline Package
Download
Pipeline One-pager
A woman in a white shirt smiles at the camera.
Dr. Julia Schulze
Research
julia.schulze@bayer.com
Therapeutic Areas
Oncology (ONC)
Cardiovascular* (CVD)
Neurology &
Rare Diseases (NRD)
Immunology (IM)
Others
PhaseAreaProgram (Mode-of-action)Indication 
IIIONCDarolutamide
(AR Inhibitor)		Adjuvant Prostate CancerSmall Molecule
IIIONCDarolutamide
(AR Inhibitor)		Prostate Cancer with
Biochemical Recurrence after
Curative Radiotherapy		Small Molecule
IIIONCSevabertinib
(HER2/mEGFR Inhibitor)		Advanced Non-small
Cell Lung Cancer with
HER2 Activating Mutations, 1L (SOHO-02)		Small_Molecule_NTE
IIICVDFinerenone
(MR Antagonist)		Non-diabetic CKD (FIND-CKD)Small Molecule
IIICVDFinerenone
(MR Antagonist)		Chronic Kidney Disease 
in Type 1 Diabetes 
FINE-ONE		Small Molecule
IIICVDVericiguat
(sGC Stimulator)		Heart Failure
(HFrEF)		Small Molecule
IIICVDAsundexian
(FXIa Inhibitor)		2⁰ Stroke Prevention
(OCEANIC Stroke)
 		Small Molecule
IIIOtherGadoquatrane
(High Relaxivity Contrast Agent)		Magnetic Resonance
Imaging (HRCA)		Contrast Agent_NTE
IIONCSevabertinib
(HER2/mEGFR Inhibitor)		Metastatic or Unresectable Solid Tumors with HER2-activating Mutations (panSOHO)Small Molecule
IICVDCongestive Heart Failure rAAV Gene Therapy (AB-1002)Congestive Heart Failure
(GenePHIT)		gene therapy
IICVDAnti-a2APAcute Ischemic Stroke;
Pulmonary Embolism		Antibody
IICVDNurandociguat
(sGC Activator Oral)		Chronic Kidney DiseaseSmall_Molecule_NTE
IINRDParkinson's Disease
rAAV Gene Therapy
(AB-1005)		Parkinson's DiseaseGene Therapy_NTE
IONCSevabertinib
(HER2/mEGFR Inhibitor)		Advanced Non-small
Cell Lung Cancer with
EGFR Mutation and/or
HER2 Mutation		Small_Molecule_NTE
IONCDGKzeta InhibitorAdvanced solid tumorsSmall_Molecule_NTE
IONCLanerkitug
(CCR8 Ab)		Advanced solid tumorsAntibody
IONCVVD Keap1 ActCancerSmall_Molecule_NTE
IONCDGKalpha InhibitorCancerSmall_Molecule_NTE
IONC225Ac-PelgifatamabAdvanced Prostate CancerRadiotherapy_NTE
IONCVVD STAT3 InhibitorCancerSmall_Molecule_NTE
IONC225Ac-PSMA-TrilliumAdvanced Prostate CancerRadiotherapy_NTE
IONCSOS1 InhibitorAdvanced Solid CancersSmall_Molecule_NTE
IONCPRMT5 InhibitorMTAP-deleted Solid TumorsSmall_Molecule_NTE
IONCVVD RAS-PI3K InhibitorAdvanced Solid TumorsSmall_Molecule_NTE
IONC225Ac-GPC3Advanced Liver CancerRadiotherapy_NTE
ICVDSEMA 3aAlport SyndromeAntibody
ICVDAnti-coagulantAnti-coagulationSmall_Molecule_NTE
ICVDAtrial fibrillationAtrial fibrillationNME
INRDBemdaneprocel
(Parkinson’s Disease
Cell Therapy)		Parkinson's DiseaseCell Therapy_NTE
INRDMultiple System Atrophy
rAAV Gene Therapy		Multiple
System Atrophy		Gene Therapy_NTE
INRDPompe Disease
rAAV Gene Therapy		Pompe DiseaseGene Therapy_NTE
INRDLGMD2I/R9
rAAV Gene Therapy		Limb Girdle
Muscular Dystrophy		Gene Therapy_NTE
IOtherGPR84 AntagonistDiabetic
Neuropathic Pain		Small_Molecule_NTE
IOtherBAY 2701250Pulmonary HypertensionProtein Therapeutics

* Including Precision Cardiovascular, Nephrology & Acute Care

Legende_pipeline

 

New Molecular Entity   New molecular entity
Life cycle management   Life cycle management

 

Derin Denham
Derin Denham
Innovation Communications
derin.denham@bayer.com
Discover more
A woman and an older woman are walking in the park.
Creating the Future You
Proactive Ways to Get Healthier as You Get Older
How we age is a collection of a number of factors. And a lot of them are in your control. Be proactive in creating the future you.
Read More
2 min read
A woman is working in a laboratory with yellow flasks.
Our engagement
Balancing act between innovative cancer medicines and generics
The Chinese government has eliminated tariffs and is reducing VAT on cancer drugs, putting more pressure on reimbursement negotiations and procurement processes to urge pharma companies to transfer this economic benefit to patients. This will put price pressure on cancer drugs, ideally without compromising on quality.
Read More
5 min read
Two women in lab coats looking at a piece of paper.
OUR ENGAGEMENT
Investing in Wellness Strategies for an Actively Aging Society
Policy changes must make way for market innovation to enhance functional ability as we age, says Michael Hodin, CEO of the Global Coalition on Aging. 30 years from now, the new metric for success in healthcare will be wellness prevention and the preservation of functional ability.
Read More
4 min read
An image of a woman looking at a dna.
OUR ENGAGEMENT
Gene Therapy May Defeat Previously Incurable Diseases | Pharmaceuticals
Gene therapy is considered the key to combating previously incurable diseases. In contrast to the traditional administration of drugs, a functional gene enables the body to produce the required proteins itself. Researchers are currently pursuing a promising approach for the treatment of hemophilia A, among other diseases.
Read More
4 min read
A woman's face is shown with a number of icons on it.
Our Engagement
Prevention is Within Reach With Artificial Intelligence
Data science and advanced analytics are driving the digitalization of healthcare systems. Smart, platform-based applications are designed to further improve the quality of medical care and provide personalized solutions to manage, treat and, ultimately, prevent disease.
Read More
5 min read
A woman with blond hair is holding a cell phone.
Our engagement
Redesigning the 100-Year-Life Society
The future of aging lies beyond standardization, according to Esko Aho, Chairman of the Board of Cinia Oy and Adven Group. From pharmaceuticals to service design, the shift towards personalization is raising our standard of living. Mr Aho believes that in thirty years, a good life will be controlled by individuals.
Read More
4 min read
A person is sitting on a chair with a robotic arm.
OUR ENGAGEMENT
Paving the Way for Progressive Healthcare
Japan is leading the way in healthcare research, development and delivery for its aging populations, says Dr. Michael Devoy, Chief Medical Officer for Bayer’s Pharmaceuticals Division. In thirty years, healthcare systems should focus on extending the maintenance of healthy, active lifestyles.
Read More
3 min read
A man and woman in lab coats are looking at something.
Precision Oncology
Targeted and Effective Tumor Therapy
Conventional cancer therapy often comes with severe side effects. With new treatment methods, some tumors can be targeted effectively, reducing these adverse effects. Read what experts are saying about precision oncology’s potential.
Read More
6 min read
An image of a doctor touching a heart.
Heart Failure
New Compounds Give Patients Hope
The figures are alarming: One in five people will develop heart failure in the course of their lives. More than 40,000 deaths a year in Germany alone are caused by a weak heart. New therapies could offer hope in the future. They are designed to strengthen the body's most important muscle and could thus potentially improve the quality of life of those affected and reduce hospital admissions and deaths.
Read More
5 min read
A close up of a person wearing colorful glasses.
OUR ENGAGEMENT
The Long Hunt For The Next Breakthrough
Only one in 10,000 active ingredients created by researchers in a lab is turned into a potential drug. But pharmaceutical research is not only expensive and time-consuming, it’s also a process liable to lead to a dead end. How drugs make the long journey from lab to market.
Read More
6 min read
An elderly woman is holding an elderly woman's hand.
OUR ENGAGEMENT
Boosting Longevity and Prosperity in Developing Nations
Developing nations are transitioning to rapidly aging societies – and in order to support their populations, governments must invest in human capital, says Annette Dixon, Vice President for Human Development at the World Bank Group. In 30 years, people must be able to be productive and active for as long as possible.
Read More
4 min read
An image of a woman's face with a robot in the background.
Transforming Healthcare. For People.
Detecting Skin Cancer in The Bathroom Mirror
The field of medicine is currently experiencing an incredible surge in innovation, driven by groundbreaking new biological discoveries, a digital revolution and a growing willingness to collaborate in research globally. What can patients expect for the future?
Read More
6 min read